Tissue Inhibitor of Metalloproteinases 3 (TIMP-3)

TIMP 3 is a member of a group of proteins that inhibit matrix metalloproteinases and thereby prevent the degradation of the extracellular matrix. TIMP 3 has a high affinity for binding the extracellular matrix. An over expression of TIMP 3 may inhibit cancer cells and tumors in certain types of cancer, including prostate cancer.

Swiss-Prot Accession Number: P35625

Responses to Bacteria, Virus and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia (2015) Valim C, Ahmad R, Lanaspa M, Tan Y, Acácio S, Gillette MA, Almendinger KD, Milner DA Jr, Madrid L, Pellé K, Harezlak J, Silterra J, Alonso PL, Carr SA, Mesirov JP, Wirth DF, Wiegand RC, Bassat Q Am J Respir Crit Care Med.