Insulin-like Growth Factor-Binding Protein 7 (IGFBP-7)

IGFBP-7 belongs subfamily of low-affinity IGFBPs. It is believed that IGFBP7 binds to unoccupied IGF1R and suppresses growth. Decreased IGFBP7expression has been seen in some cancers. High grade invasive breast cancers lack IGFBP7 expression.

Swiss-Prot Accession Number: Q16270

Myriad RBM Publications Publications
Biomarker panels associated with progression of renal disease in type 1 diabetes. (2019) Colombo M, Valo E, McGurnaghan SJ, Sandholm N, Blackbourn LAK, Dalton RN, Dunger D, Groop PH, McKeigue PM, Forsblom C, Colhoun HM Diabetologia