Prostasin

Prostasin is a serine proteinase originally isolated from human seminal fluid. Prostasin was detected by immunostaining more strongly in cancerous ovarian epithelial cells and stromal cells than in normal ovarian tissue. Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus, and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.

Swiss-Prot Accession Number: Q16651


 
Therapy Indications
 
Publications
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
Proteomic biomarkers of cognitive impairment in obstructive sleep apnea syndrome (2018) Lal C, Hardiman G, Kumbhare S, Strange C Sleep and Breathing
Variation in Serum Biomarkers with Sex and Female Hormonal Status: Implications for Clinical Tests (2016) Ramsey JM, Cooper JD, Penninx BWJH, Bahn S Scientific Reports
Serum Proteomic Profiling of Major Depressive Disorder (2015) Bot M, Chan MK, Jansen R, Lamers F, Vogelzangs N, Steiner J, Leweke FM, Rothermundt M, Cooper J, Bahn S, Penninx BWJH Translational Psychiatry
Multiplexed protein profiling after bariatric surgery: characterization of improved endothelial dysfunction (2013) Bachmayer C, Hammes HP, Hasenberg T, Lammert A, Crowther D, Hess S Experimental and Clinical Endocrinology & Diabetes
Comprehensive serum profiling for the discovery of epithelial ovarian cancer biomarkers (2011) Yip P, Chen TH, Seshaiah P, Stephen LL, Michael-Ballard KL, Mapes JP, Mansfield BC, Bertenshaw GP PLoS One. 2011;6(12):e29533. Epub 2011 Dec 21