Interleukin-6 receptor subunit beta (IL-6R beta)

Interleukin-6 receptor subunit beta (IL-6R beta; gp130, IL-6Rß) is a transmembrane glycoprotein that is a subunit constituent of several cytokine receptors, including those for IL-6, IL-11, LIF, Oncostatin M, and CNTF. Soluble forms of IL-6R beta with molecular masses of 90 and 110 kDa have been found in serum. They can inhibit biological functions of those cytokines utilizing receptor systems with IL-6R beta as a component.

Swiss-Prot Accession Number: P40189


 
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Myriad RBM Publications Publications
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
Carbon nanotube and nanofiber exposure and sputum and blood biomarkers of early effect among U.S. workers (2018) Beard JD, Erdely A, Dahm MM, de Perio MA, Birch ME, Evans DE, Fernback JE, Eye T, Kodali V, Mercer RR, Bertke SJ, Schubauer-Berigan MK Environmental Internation 116 (2018)
Variation in Serum Biomarkers with Sex and Female Hormonal Status: Implications for Clinical Tests (2016) Ramsey JM, Cooper JD, Penninx BWJH, Bahn S Scientific Reports