Interferon gamma Induced Protein 10 (IP-10)
Interferon gamma Induced Protein 10 (IP-10; 10kDa interferon-gamma-induced protein; CXCL10) is induced in a variety of cells in response to IFN-gamma. IP-10 inhibits bone marrow colony formation and angiogenesis, stimulates NK and T cell migration, regulates T cell maturation, and modulates adhesion molecule expression. IP-10 expression has been associated with HIV infection and levels have been shown to be elevated in patients with Alzheimer’s disease.
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Publications Mesenteric Ischemia-Reperfusion Injury up-Regulates Certain Cc, Cxc, and Xc Chemokines and Results in Multi-Organ Injury in a Time-Dependent Manner
(2013) Jawa RS, Quist E, Boyer CW, Shostrom VK, Mercer DW European Cytokine Network
Inflammatory Mediator Profiling Reveals Immune Properties of Chemotactic Gradients and Macrophage Mediator Production Inhibition During Thioglycollate Elicited Peritoneal Inflammation
(2013) Lam D, Harris D, Qin Z Mediators of Inflammation