Macrophage Colony-Stimulating Factor 1 (M-CSF)

Macrophage colony-stimulating factor (M-CSF) was initially described as a factor that stimulates the growth of colonies of macrophages and granulocytes in soft agar. M-CSF influences the proliferation and differentiation of hematopoietic stem cells into macrophages and also the growth survival and differentiation of monocytes. In addition to its role in inflammation, M-CSF has been shown to play a role in adipocyte hyperplasia.

Swiss-Prot Accession Number: P09603


Myriad RBM Publications Publications
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease (2018) Sjaarda J, Gerstein H, Chong M, Yusuf S, Meyre D, Anand SS, Hess S, Pare G Journal of the American College of Cardiology
Sjögren’s Syndrome Patients with Ectopic Germinal Centers Present with a Distinct Salivary Proteome (2016) Delaleu N, Mydel P, Brun JG, Jonsson MV, Alimonti A, Jonsson R Rheumatology
Circulating Biomarkers and Outcome from a Randomised Phase Ii Trial of Sunitinib Vs Everolimus for Patients with Metastatic Renal Cell Carcinoma (2016) Voss MH, Chen D, Marker M, Hakimi AA, Lee C-H, Hsieh JJ, Knox JJ, Voi M, Motzer RJ British Journal of Cancer
Variation in Serum Biomarkers with Sex and Female Hormonal Status: Implications for Clinical Tests (2016) Ramsey JM, Cooper JD, Penninx BWJH, Bahn S Scientific Reports
Serum Proteomic Profiling of Major Depressive Disorder (2015) Bot M, Chan MK, Jansen R, Lamers F, Vogelzangs N, Steiner J, Leweke FM, Rothermundt M, Cooper J, Bahn S, Penninx BWJH Translational Psychiatry
Heart Failure Therapy Mediated by the Trophic Activities of Bone Marrow Mesenchymal Stem Cells: A Non-invasive Therapeutic Regimen. (2009) Shabbir A, Zisa D, Suzuki G, Lee T Am J Physiol Heart Circ Physiol 296: H1888-H1897.