This page contains an up-to-date list of the important changes to Myriad RBM’s products and assays. These changes are made as part of our ongoing efforts to improve the quality of our assays and the data we provide. We strive to deliver superior services by emphasizing reliable data and aim to make customers aware of information that may impact their projects as soon as possible.

If you have questions about any of the items contained in the following tables, please contact Myriad RBM’s Client Services team

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2019

Quarter 2

Assay or ProductDescription of ChangeEffective Date
Apolipoprotein E (Apo E)Assay discontinued from human services.17-Jun-19
Follicle-Stimulating Hormone (FSH)Assay adjusted to meet industry standards.31-May-19
Oncostatin-M Simoa (OSM Simoa)Assay added to service offerings.06-May-19
Oncostatin-M-specific receptor subunit beta Simoa (OSMR Simoa)Assay added to service offering.06-May-19
Tumor Necrosis Factor Ligand Superfamily Member 14 Total Simoa (LIGHT Total Simoa)Assay added to service offerings. 06-May-19
Apolipoprotein B (Apo B)Assay discontinued from human services.18-Apr-19

Quarter 1

Assay or ProductDescription of ChangeEffective Date
Apolipoprotein(a) (Lp(a))Assay was redeveloped using a new antigen.07-Mar-19
E-SelectinAssay blocker formulation was adjusted.10-Jan-19
Monocyte Chemotactic Protein 2 (MCP-2)Assay blocker formulation was adjusted.10-Jan-19
Interleukin-6 receptor (IL-6r)Assay blocker formulation was adjusted.10-Jan-19
Monocyte Chemotactic Protein 4 (MCP-4)Assay blocker formulation was adjusted.10-Jan-19
Macrophage Inflammatory Protein-3 alpha (MIP-3 alpha)Assay blocker formulation was adjusted.10-Jan-19
Myeloid Progenitor Inhibitory Factor 1 (MPIF-1) Assay blocker formulation was adjusted.10-Jan-19
Monokine Induced by Gamma Interferon (MIG)Assay moved to a different multiplex.10-Jan-19
Interferon gamma Induced Protein 10 (IP-10)Assay moved to a different multiplex.10-Jan-19
Tissue type Plasminogen activator (tPA) Assay was redeveloped using a new antigen.11-Jan-19
Urokinase-type Plasminogen Activator (uPA)Assay was redeveloped using a new antigen.11-Jan-19
Galectin-3Assay does not meet performance specifications in EDTA plasma.11-Jan-19

2018

Quarter 4

Assay or ProductDescription of ChangeEffective Date
AdiponectinAssay discontinued from human services.13-Dec-18
Interleukin-13 Simoa (IL-13 Simoa)Assay added to service offerings.7-Dec-18
Interleukin-17C Simoa (IL-17C Simoa)Assay added to service offerings.7-Dec-18
Interleukin-8 (IL-8)Assay moved to a different multiplex.29-Nov-18
Cellular Fibronectin (cFIB)Assay discontinued from human services.29-Nov-18
Interleukin-9 Simoa (IL-9 Simoa)Assay added to service offerings.26-Nov-18
Receptor Activator of Nuclear Factor Kappa B Ligand Simoa (RANKL Simoa)Assay added to service offerings.14-Nov-18
Tumor Necrosis Factor Ligand Superfamily Member 14 Simoa (LIGHT, free Simoa)Assay added to service offerings.14-Nov-18
Interleukin-8 Simoa (IL-8 Simoa)Assay added to service offerings.16-Oct-18
Interleukin-8 (IL-8)Assay moved to a different multiplex.11-Oct-18

Quarter 3

Assay or ProductDescription of ChangeEffective Date
Thymus-Expressed Chemokine (TECK)Assay was redeveloped using a new antigen.14-Sept-18
Apolipoprotein D (Apo D)Assay redeveloped with new capture and detection antibodies.23-Aug-18
Interleukin-18 binding protein (IL-18bp)Assay redeveloped with a new antigen.15-Aug-18
OsteocalcinAssay meets performance specifications in EDTA plasma.02-Aug-18
ST2Assay meets performance specifications in Serum.02-Aug-18
CD163Assay redeveloped with new antigen.02-Aug-18
CD163 Assay discontinued from human services. 03-Jul-18
OsteocalcinAssay does not meet performance specifications in EDTA plasma. 03-Jul-18
ST2 Assay does not meet performance specifications in Serum. 03-Jul-18

Quarter 2

Assay or ProductDescription of ChangeEffective Date
Transforming Growth Factor beta-3 (TGF-beta 3) Assay discontinued from human services. 04-Apr-18

Quarter 1

Assay or ProductDescription of ChangeEffective Date
VaspinAssay was redeveloped using a new capture antibody. 20-Mar-18
OmentinAssay does not meets performance specifications in Serum. 20-Mar-18
Cartilage Oligomeric Matrix Protein (COMP)Assay added to human services. 09-Mar-18
Alpha-1-Microglobulin (A1Micro, urine)Assay discontinued from human services.06-Mar-18
Tamm-Horsfall Urinary Glycoprotein (THP, urine)Assay discontinued from human services.06-Mar-18
Trefoil Factor 3 (TFF3, urine)Assay discontinued from human services.06-Mar-18
Interferon-alpha (IFN-alpha)Assay redeveloped with new capture and detection antibodies.21-Feb-18
CD27 antigen (CD27)Assay redeveloped with a new antigen.06-Feb-18
CD27 antigen (CD27)Assay blocker formulation was adjusted.06-Feb-18
Fibroblast Growth Factor 21 (FGF-21)Assay blocker formulation was adjusted.06-Feb-18
Fibroblast growth factor 23 (FGF-23)Assay blocker formulation was adjusted.06-Feb-18
Insulin-like Growth Factor-Binding Protein 7 (IGFBP-7)Assay blocker formulation was adjusted.06-Feb-18
Interleukin-1 receptor type 1 IL-1RIAssay blocker formulation was adjusted.06-Feb-18
ProgranulinAssay blocker formulation was adjusted.06-Feb-18
Thymus-Expressed Chemokine (TECK)Assay blocker formulation was adjusted.06-Feb-18
Thymus-Expressed Chemokine (TECK)Assay blocker formulation was adjusted.06-Feb-18
Tissue Inhibitor of Metalloproteinases 3 (TIMP-3)Assay blocker formulation was adjusted.06-Feb-18
Interleukin-18-binding protein (IL-18bp)Assay discontinued from human services.26-Jan-18
Angiopoietin-1 (ANG-1)Assay meets performance specifications in EDTA plasma.25-Jan-18
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)Assay meets performance specifications in serum.25-Jan-18
Serum Amyloid A Protein (SAA)Assay meets performance specifications in serum.19-Jan-18
Ficolin-3Assay redeveloped using a new capture antibody.19-Jan-18
Neutrophil Activating Peptide 2 (NAP-2)Assay redeveloped using a new capture antibody.19-Jan-18
Serum Amyloid A Protein (SAA)Assay redeveloped using new capture and detection antibodies.19-Jan-18

2017

Quarter 4

Assay or ProductDescription of ChangeEffective Date
Amphiregulin (AR)Assay blocker formulation was adjusted.06-Nov-17
Epidermal Growth Factor (EGF)Assay blocker formulation was adjusted.06-Nov-17
Epidermal Growth Factor Receptor (EGFR)Assay blocker formulation was adjusted.06-Nov-17
Epiregulin (EPR)Assay blocker formulation was adjusted.06-Nov-17
Heparin-Binding EGF-Like Growth Factor (HB-EGF)Assay blocker formulation was adjusted.06-Nov-17
Placenta Growth Factor (PLGF)Assay blocker formulation was adjusted.06-Nov-17
Platelet-Derived Growth Factor BB (PDGF-BB)Assay blocker formulation was adjusted.06-Nov-17
Tenascin-C (TN-C)Assay blocker formulation was adjusted.06-Nov-17

Quarter 3

Assay or ProductDescription of ChangeEffective Date
Growth/differential factor 11 Simoa (GDF-11)Assay added to human services.30-Aug-17
Neurofilament Light Chain Simoa (NF-L)Assay added to human services.24-Aug-17
TruCulture OptiMAP™ v. 1.0Product added to human services.23-Aug-17

Quarter 2

Assay or ProductDescription of ChangeEffective Date
Serum Amyloid P-Component (SAP)Assay moved to a different multiplex.22-Jun-17
CD40 Antigen (CD40)Assay added to human services.08-Jun-17
Macrophage Migration Inhibitory Factor (MIF)Assay redeveloped with a new antigen.06-Jun-17
Kidney Injury Molecule-1 Simoa (KIM-1)Assay added to human services.30-May-17
Immunoglobulin E (IgE)Assay added to human services.25-May-17
Amphiregulin Simoa (AR)Assay added to human services.18-May-17
Apolipoprotein B (Apo B)Assay added to human services.17-May-17
Human OncologyMAP v. 3.0 Product discontinued from human services.3-Apr-17
HE4 Assay adjusted to meet industry standards.24-Apr-17
Apolipoprotein B (Apo B)Assay discontinued from all human services.17-Apr-17
AdiponectinAssay added to human services.13-Apr-17
Interleukin-31 Simoa (IL-31)Assay added to human services.13-Apr-17
AdiponectinAssay discontinued from all human services.03-Apr-17
Serotransferrin (Transferrin)Assay added to human services.03-Apr-17
Monocyte Chemotactic Protein (MCP-4)Assay adjusted to meet industry standards.03-Apr-17

Quarter 1

Assay or ProductDescription of ChangeEffective Date
Interferon-alpha Simoa (IFN-a)Assay added to human services.23-Jan-17
OsteocalcinAssay added to human services.10-Feb-17
Immunoglobulin E (IgE)Assay discontinued from all human services.24-Jan-17
Aldose ReductaseAssay discontinued from all human services.12-Jan-17
Glutathione S-Transferase Mu 1 (GST-M1)Assay discontinued from all human services.12-Jan-17
Peroxiredoxin-4 (Prx-IV)Assay discontinued from all human services.12-Jan-17
Phosphoserine Aminotransferase (PSAT)Assay discontinued from all human services.12-Jan-17
Lactoylglutathione lyase (LGL)Assay discontinued from all human services.12-Jan-17
Squamous Cell Carcinoma Antigen-1 (SSCA-1)Assay discontinued from all human services.12-Jan-17
Vascular Endothelial Growth Factor Receptor 3 (VEGFR-3) Assay added to human services.09-Jan-17

2016

Quarter 4

Assay or ProductDescription of ChangeEffective Date
Mesothelin (MSLN)Assay discontinued from all human services.21-Dec-16
Growth/differentiation factor 11 (GDF-11)Assay discontinued from all human services.13-Dec-16
Hepatocyte Growth Factor (HGF)Assay added to human services.04-Nov-16
Beta-microseminoprotein (PSP94)Assay discontinued from all human services.21-Oct-16
Cystatin-AAssay discontinued from all human services.21-Oct-16
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)Assay discontinued from all human services.21-Oct-16
Cathepsin B (pro) (CTSB)Assay discontinued from all human services.21-Oct-16
Tenascin-X (TN-X)Assay discontinued from all human services.21-Oct-16
Lipocalin-1 (LCN1)Assay discontinued from all human services.21-Oct-16
Prostate Specific Antigen, total (tPSA)Assay discontinued from all human services.21-Oct-16
Interleukin-4 (IL-4)Assay added to human services.10-Oct-16
Fibulin-1C (Fib-1C)Assay redeveloped using a new standard.06-Oct-16

Quarter 3

Assay or ProductDescription of ChangeEffective Date
Interleukin-4 (IL-4)Assay discontinued from all human services.08-Sep-16
CeruloplasminAssay discontinued from all human services.01-Sep-16
Granulocyte Colony-Stimulating Factor Simoa (G-CSF)Assay added to human services.26-Aug-16
Interleukin-12 Subunit p40 Simoa (IL-12p40)Assay added to human services.16-Aug-16
Dipeptidyl peptidase IV (DPPIV)Assay discontinued from all human services.12-Aug-16
Monokine Induced by Gamma Interferon (MIG)Assay added to human services.26-Jul-16
Collagen IVAssay redeveloped using a new detection antibody.01-Jul-16

Quarter 2

Assay or ProductDescription of ChangeEffective Date
Immunoglobulin E (IgE)Assay redeveloped using a new antigen.28-Jun-16
PeriostinAssay redeveloped using a new antibody pair.23-Jun-16
P-SelectinAssay does not meets performance specifications in EDTA plasma.23-Jun-16
OsteocalcinAssay discontinued from all human services.23-Jun-16
Urokinase-type Plasminogen Activator (uPA)Assay meets performance specifications in EDTA plasma.17-Jun-16
Secreted protein acidic and rich in cysteine (SPARC)Assay discontinued from human services.09-May-16
Interleukin-4 (IL-4)Assay added to human services.06-May-16
Serum Amyloid P-Component (SAP)Assay added to human services.15-Apr-16
Chromogranin-A (CgA)Assay blocker formulation was adjusted.7-Apr-16
Nerve Growth Factor beta (NGF-beta)Assay blocker formulation was adjusted.7-Apr-16
Neuronal Cell Adhesion Molecule (Nr-CAM)Assay blocker formulation was adjusted.7-Apr-16
S100 calcium-binding protein B (S100-B)Assay blocker formulation was adjusted.7-Apr-16
SortilinAssay blocker formulation was adjusted.7-Apr-16
Receptor for advanced glycosylation end products (RAGE)Assay blocker formulation was adjusted.7-Apr-16
Superoxide Dismutase 1, soluble (SOD-1)Assay blocker formulation was adjusted.7-Apr-16

Quarter 1

Assay or ProductDescription of ChangeEffective Date
Interleukin-4 (IL-4)Assay temporarily discontinued from all human services.22-Mar-16
Monokine Induced by Gamma Interferon (MIG)Assay temporarily discontinued from all human services.14-Mar-16
Vascular Endothelial Growth Factor Receptor 3 (VEGFR-3)Assay discontinued from all human services.01-Mar-16
Hepatocyte Growth Factor (HGF)Assay discontinued from all human services.01-Mar-16
Urokinase-type plasminogen activator receptor (uPar)Assay redeveloped using a new antibody pair.26-Feb-16
Serum Amyloid P Component (SAP)Assay discontinued from all human services.26-Feb-16
Secreted protein acidic and rich in cysteine (SPARC)Assay meets performance specifications in EDTA plasma.16-Feb-16
Vascular endothelial growth factor D (VEGF-D)Assay redeveloped using a new antibody part number.16-Feb-16
C-ReactiveAssay discontinued from all rodent services.01-Feb-16
FibrinogenAssay discontinued from all rodent services.01-Feb-16
Serum Amyloid P-ComponentAssay discontinued from all rodent services.01-Feb-16
OsteocalcinAssay redeveloped using new antigen.26-Jan-16
Interleukin-2 Simoa (IL-2)Assay added to human services.26-Jan-16
Insulin-like Growth Factor-Binding Protein 3Assay discontinued from human services.13-Jan-16
Insulin-like Growth Factor-Binding Protein 4Assay discontinued from human services.13-Jan-16
Insulin-like Growth Factor-Binding Protein 5Assay discontinued from human services.13-Jan-16
Insulin-like Growth Factor-Binding Protein 6Assay discontinued from human services.13-Jan-16
A disintegrin and metalloproteinase with thrombospondin motifs 8Assay added to human services.11-Jan-16
Folate receptor gammaAssay added to human services.11-Jan-16
Growth/differentiation factor 11Assay added to human services.11-Jan-16
Aggrecan core proteinAssay added to human services.11-Jan-16
C-C motif chemokineAssay added to human services.11-Jan-16
UteroglobinAssay added to human services.11-Jan-16

2015

Quarter 4

Assay or ProductDescription of ChangeEffective Date
CD40 antigenAssay discontinued from human services.16-Dec-15
VitronectinAssay added to human services.16-Dec-15
SerotransferrinAssay discontinued from human services.15-Dec-15
Pentraxin-3Assay discontinued from human services.11-Dec-15
Glycogen phosphorylase isoenzyme BBAssay added to human services.11-Dec-15
Interleukin-13Assay redeveloped using new antigen.07-Dec-15
Alpha-1-AntichymotrypsinAssay discontinued from all human services.30-Nov-15
Apolipoprotein A-IVAssay discontinued from all human services.30-Nov-15
Heat Shock Protein 60Assay discontinued from all human services.30-Nov-15
Proinsulin, intactAssay discontinued from all human services.30-Nov-15
Proinsulin, totalAssay discontinued from all human services.30-Nov-15
Fibroblast Growth Factor-basicAssay discontinued from all human services.30-Nov-15
Cartilage Oligomeric Matrix ProteinAssay discontinued from all human services.30-Nov-15
Complement component C1q receptorAssay discontinued from all human services.30-Nov-15
ChemerinAssay discontinued from all human services.30-Nov-15
Selenoprotein PAssay discontinued from all human services.30-Nov-15
Angiopoietin-related protein 3Assay discontinued from all human services.30-Nov-15
Peptidase DAssay discontinued from all human services.30-Nov-15
Thrombospondin-4Assay discontinued from all human services.30-Nov-15
Interleukin-5 Simoa (IL-5)Assay added to human services.27-Oct-15
ThyroglobulinAssay redeveloped using a new capture and detection antibody.23-Oct-15
Peroxiredoxin-4Assay added to human services.15-Oct-15
Tissue Inhibitor of Metalloproteinases 1Assay discontinued from human services (urine products only).15-Oct-15

Quarter 3

Assay or ProductDescription of ChangeEffective Date
Angiopoietin-related protein 4Assay added to human services.23-July-15
Bone morphogenetic protein 9Assay added to human services.23-July-15
SclerostinAssay added to human services.23-July-15
Secreted protein acidic and rich in cysteineAssay added to human services.23-July-15
MidkineAssay discontinued from all human services.17-July-15

Quarter 2

Assay or ProductDescription of ChangeEffective Date
Glycogen phosphorylase isoenzyme BBAssay discontinued from all human services.17-Jun-15
Complement C3 (C3)Assay discontinued from all human services.17-Jun-15
Peroxiredoxin-4Assay discontinued from all human services.17-Jun-15
Apolipoprotein A-IAssay added to human services.11-Jun-15
Vascular Endothelial Growth Factor C (VEGF-C)Assay discontinued from all human or mouse services.11-Jun-15
Sex Hormone-Binding Globulin (SHBG)Assay moved to a different multiplex.29-Apr-15
Leucine-Rich Alpha-2-Glycoprotein (LRG1)Assay discontinued from all human services.29-Apr-15
Serum Amyloid A Protein (SAA)Assay did not meet performance specifications in serum and results should be used for information purposes only.17-Apr-15
Alpha-2-Macroglobulin (A2M)Assay meets performance specifications in plasma EDTA.15-Apr-15
Interferon Gamma Simoa (IGN-g)Assay added to human services.6-Apr-15

Quarter 1

Assay or ProductDescription of ChangeEffective Date
Interleukin-1 beta Simoa (IL-1 b)Assay added to human services.31-Mar-15
Interleukin-10 Simoa (IL-10)Assay added to human services.31-Mar-15
ClusterinAssay redeveloped using new antigen.20-Mar-15
Creatine Kinase (CK-MB)Assay discontinued from human services.19-Mar-15
GLP-1 activeAssay discontinued from human services.12-Mar-15
InsulinAssay added to human services.12-Mar-15
LumicanAssay discontinued from human services.6-Mar-15
Tumor Necrosis Factor-alpha (TNF-α)Assay added to human services.4-Mar-15
Interleukin-6 Simoa (IL-6)Assay added to human services.4-Mar-15
Cadherin-13 (T-cad)Assay added to human services.24-Feb-15
MidkineAssay added to human services.24-Feb-15
ApopotosisMAP 1.0Product discontinued from human services.18-Feb-15
InsulinAssay discontinued from all human services.11-Feb-15
Peroxiredoxin-4 (Prx-IV)Assay added to human services.9-Feb-15
Protein S100-A6 (S100-A6)Assay added to human services.9-Feb-15
Glucose-6-phosphate Isomerase (G6PI)Assay moved to a different multiplex9-Feb-15
Lactoylglutathione lyase (LGL)Assay moved to a different multiplex9-Feb-15
Squamous Cell Carcinoma Antigen-1 (SCCA-1)Assay moved to a different multiplex9-Feb-15
Phosphoserine Aminotransferase (PSAT)Assay moved to a different multiplex9-Feb-15
Glutathione S-Transferase Mu 1 (GST-M1)Assay moved to a different multiplex9-Feb-15
Epithelial cell adhesion molecule (EpCam)Assay moved to a different multiplex9-Feb-15
Aldose ReductaseAssay moved to a different multiplex9-Feb-15
Protein S100-A4 (S100-A4)Assay discontinued from all human services.9-Feb-15
DiscoveryMAP 175+Product discontinued from human services.3-Feb-15
DiscoveryMAP 250+Product discontinued from human services.3-Feb-15
ExplorerMAPProduct added to human services.3-Feb-15

2014

Quarter 4

Assay or ProductDescription of ChangeEffective Date
Complement C3 (C3)Assay discontinued from all human services29-Dec-14
Glutathione S-Transferase alpha (GST-alpha)Assay discontinued from all human services24-Nov-14
Secreted Protein Acidic and Rich in Cysteine (SPARC)Assay did not meet performance specifications in plasma and results should be used for information purposes only.11-Nov-14
RANTESAssay discontinued from all rodent services.16-Oct-14
VitronectinAssay discontinued from all human services.15-Oct-14
Beta Amyloid1-40 (AB 40)Assay adjusted to meet industry standards.08-Oct-14
Beta Amyloid 1-42 (AB-42)Assay adjusted to meet industry standards.08-Oct-14
LymphotactinAssay discontinued from all rodent services.07-Oct-14
Lipocalin-1 (LCN-1)Assay added to human services07-Oct-14

Quarter 3

Assay or ProductDescription of ChangeEffective Date
PYYAssay discontinued from all human services.23-Sep-14
Antithrombin-IIIAssay added to CardiovascularMAP05-Sep-14
Ficolin-3Assay added to CardiovascularMAP05-Sep-14
Neurpilin-1Assay added to CardiovascularMAP05-Sep-14
Neutrophil Activating Peptide 2Assay added to CardiovascularMAP05-Sep-14
Pigment Epithelium Derived FactorAssay added to CardiovascularMAP05-Sep-14
Serum Amyloid A ProteinAssay added to CardiovascularMAP05-Sep-14
Thrombin-Activatable FibrinolysisAssay added to CardiovascularMAP05-Sep-14
OsteopontinAssay removed from CardiovascularMAP05-Sep-14
GlucagonAssay discontinued from all human services05-Sep-14
Receptor tyrosine-protein kinase erbB-3Assay did not meet specifications in EDTA plasma05-Sep-14
Fatty Acid-Binding Protein, adipocyteAssay did not meet specifications in serum05-Sep-14
Galectin-3Assay redeveloped using new antibody pair05-Sep-14
All human productsAssay ranges updated28-Aug-14
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)Multiplex buffer composition adjusted.27-Aug-14
Interferon gamma (IFN-gamma)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-10 (IL-10)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-18 (IL-18)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-2 (IL-2)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-3 (IL-3)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-4 (IL-4)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-5 (IL-5)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-6 (IL-6)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-7 (IL-7)Multiplex buffer composition adjusted.27-Aug-14
Interleukin-8 (IL-8)Multiplex buffer composition adjusted.27-Aug-14
Macrophage Inflammatory Protein-1 alpha (MIP-1 alpha)Multiplex buffer composition adjusted.27-Aug-14
Macrophage Inflammatory Protein-1 beta (MIP-1 beta)Multiplex buffer composition adjusted.27-Aug-14
Monocyte Chemotactic Protein 1 (MCP-1)Multiplex buffer composition adjusted.27-Aug-14
Tumor Necrosis Factor alpha (TNF-alpha)Multiplex buffer composition adjusted.27-Aug-14
Tumor Necrosis Factor beta (TNF-beta)Multiplex buffer composition adjusted.27-Aug-14
Human NeuroMAP™ v. 1.0Product added to human services08-Aug-14
CortisolAssay adjusted to meet industry standards.06-Aug-14
CD 40 antigen (CD40)Multiplex buffer composition adjusted.04-Aug-14
CD40 Ligand (CD40-L)Multiplex buffer composition adjusted.04-Aug-14
Erythropoietin (EPO)Assay added to human services04-Aug-14
Myeloperoxidase (MPO)Assay moved to a different multiplex.04-Aug-14
Granulocyte Colony-Stimulating Factor (G-CSF)Multiplex buffer composition adjusted.04-Aug-14
Alpha-Fetoprotein (AFP)Assay adjusted to meet industry standards.08-Aug-14
Cancer Antigen 125 (CA 125)Assay adjusted to meet industry standards.04-Aug-14
Antithrombin-III (AT-III)Multiplex buffer composition adjusted.04-Aug-14
Ficolin-3Multiplex buffer composition adjusted.04-Aug-14
Leucine-rich alpha-2-glycoprotein (LRG1)Multiplex buffer composition adjusted.04-Aug-14
Neutrophil Activating Peptide 2 (NAP-2)Multiplex buffer composition adjusted.04-Aug-14
Pigment Epithelium Derived Factor (PEDF)Multiplex buffer composition adjusted.04-Aug-14
Serum Amyloid A Protein (SAP)Multiplex buffer composition adjusted.04-Aug-14
Thrombin-activable fibrinolysis inhibitor (TAFI)Multiplex buffer composition adjusted.04-Aug-14
Neuropilin-1Assay moved to a different multiplex.04-Aug-14

Quarter 2

Assay or ProductDescription of ChangeEffective Date
CD40Assay discontinued from all rodent services27-June-14
Myeloperoxidase (MPO)Assay discontinued from all rodent services27-June-14
CD40 Ligand (CD40-L)Assay discontinued from all rodent services27-June-14
Complement Factor H Related Protein 1 (CFHR1)Assay moved to a different multiplex20-June-14
Complement Factor H Related Protein 1 (CFHR1)Assay removed from Human DiscoveryMAP 175+, Human DiscoveryMAP 250+20-June-14
Canine KidneyMAPProduct removed from rodent services05-June-14
Rat MetabolicMAPProduct removed from rodent services05-June-14
Apolipoprotein C-I (Apo C-I)Assay added to CardiovascularMAP06-May-14
Chromogranin-A (CgA)Assay added to CardiovascularMAP06-May-14
Factor VIIAssay added to CardiovascularMAP06-May-14
Fetuin-AAssay added to CardiovascularMAP06-May-14
Glucagon-like Peptide 1, active (GLP-1 active)Assay added to CardiovascularMAP06-May-14
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)Assay added to CardiovascularMAP06-May-14
InsulinAssay added to CardiovascularMAP06-May-14
Interferon gamma (IFN-gamma)Assay added to CardiovascularMAP06-May-14
Interferon gamma Induced Protein 10 (IP-10)Assay added to CardiovascularMAP06-May-14
Interleukin-1 alpha (IL-1 alpha)Assay added to CardiovascularMAP06-May-14
Interleukin-1 beta (IL-1 beta)Assay added to CardiovascularMAP06-May-14
Interleukin-6 receptor (IL-6r)Assay added to CardiovascularMAP06-May-14
Interleukin-10 (IL-10)Assay added to CardiovascularMAP06-May-14
Matrix Metalloproteinase-9 (MMP-9)Assay added to CardiovascularMAP06-May-14
Serotransferrin (Transferrin)Assay added to CardiovascularMAP06-May-14
Vascular Endothelial Growth Factor (VEGF)Assay added to CardiovascularMAP06-May-14
Vitamin K-Dependent Protein S (VKDPS)Assay added to CardiovascularMAP06-May-14
AdiponectinAssay added to OncologyMAP06-May-14
Alpha-2-Macroglobulin (A2Macro)Assay added to OncologyMAP06-May-14
Angiopoietin-2 (ANG-2)Assay added to OncologyMAP06-May-14
AXL Receptor Tyrosine Kinase (AXL)Assay added to OncologyMAP06-May-14
Beta-2-Microglobulin (B2M)Assay added to OncologyMAP06-May-14
Ciliary Neurotrophic Factor (CNTF)Assay added to OncologyMAP06-May-14
Fas Ligand (FasL)Assay added to OncologyMAP06-May-14
FASLG Receptor (FAS)Assay added to OncologyMAP06-May-14
Ferritin (FRTN)Assay added to OncologyMAP06-May-14
Fibroblast Growth Factor 4 (FGF-4)Assay added to OncologyMAP06-May-14
InsulinAssay added to OncologyMAP06-May-14
Interleukin-6 receptor (IL-6r)Assay added to OncologyMAP06-May-14
Monocyte Chemotactic Protein 3 (MCP-3)Assay added to OncologyMAP06-May-14
Plasminogen Activator Inhibitor 1 (PAI-1)Assay added to OncologyMAP06-May-14
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1)Assay added to OncologyMAP06-May-14
TNF-Related Apoptosis-Inducing Ligand Receptor 3 (TRAIL-R3)Assay added to OncologyMAP06-May-14
Transforming Growth Factor beta-3 (TGF-beta-3)Assay added to OncologyMAP06-May-14
Tumor necrosis factor receptor 2 (TNFR2)Assay added to OncologyMAP06-May-14
Vascular Cell Adhesion Molecule-1 (VCAM-1)Assay added to OncologyMAP06-May-14
Rat KidneyMAP v. 1.0Product removed from rodent services06-May-14
Bio-Plex Pro™ RBM Rat Kidney Toxicity ServiceProduct added to rodent services06-May-14
Factor VIIAssay discontinued from all rodent products06-May-14
AdrenomedullinAssay added to human services06-May-14
Beta Amyloid 1-40Assay added to human services06-May-14
Beta Amyloid 1-42Assay added to human services06-May-14
Dopamine beta-hydroxylaseAssay added to human services06-May-14
Heat-Shock protein 70Assay added to human services06-May-14
Neurofilament heavy polypeptideAssay added to human services06-May-14
Protein DJ-1Assay added to human services06-May-14
HE4Assay redeveloped using new antibody pair.01-May-14
CA 72-4Assay discontinued from all human products03-Apr-14

Quarter 1

AssayDescription of ChangeEffective Date
AACTAssay redeveloped using new antigen.27-Mar-14
Apolipoprotein A4Assay redeveloped using new antigen.27-Mar-14
HSP60Assay redeveloped using new antigen.27-Mar-14
Proinsulin (Total)Assay redeveloped using new antigen.27-Mar-14
Proinsulin (Intact)Assay redeveloped using new antigen.27-Mar-14
MidkineAssay discontinued from all human services.27-Mar-14
TIE-1Assay discontinued from all human products.20-Mar-14
Urokinase-type Plasminogen Activator (uPA)This assay did not meet performance specifications in EDTA-plasma and results should be used for information purposes only.10-Mar-14
Lipocalin 1 (LCN1)Assay discontinued from all human products.28-Feb-14
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)Assay redeveloped using new antibody pair.28-Feb-14
tPAAssay redeveloped using new antibody pair.28-Feb-14
Pulmonary and Activation-Regulated ChemokineAssay moved to a different multiplex.24-Jan-14
Matrix Metalloproteinase-2 (MMP2)Assay moved to a different multiplex.24-Jan-14
EN-RAGEAssay moved to a different multiplex and now meets performance specifications in both serum and EDTA-plasma.24-Jan-14
MHC class I chain-related protein A (MICA)Assay moved to a different multiplex.23-Jan-14
Apolipoprotein B (Apo B)Multiplex buffer composition adjusted.14-Jan-14
CD5 Antigen-like (CD5L)Multiplex buffer composition adjusted.14-Jan-14
Clusterin (CLU)Assay dilution adjusted.14-Jan-14
Complement factor H-related protein 1 (CFHR1)Multiplex buffer composition adjusted.14-Jan-14
Fetuin AMultiplex buffer composition adjusted.14-Jan-14
Growth-regulated protein alpha (GRO-alpha)Assay moved to a different multiplex.14-Jan-14
Leptin RAssay redeveloped using new antibody pair.14-Jan-14
ProgranulinAssay moved to a different multiplex.14-Jan-14
Thrombin-activatable fibrinolysis inhibitor (TAFI )Assay redeveloped using new antibody pair.14-Jan-14
Vitamin K-Dependent Protein S (VKDPS)Assay redeveloped using new antibody pair. Multiplex buffer composition adjusted.14-Jan-14
Beta-2-MicroglobulinAssay moved to a different multiplex.13-Jan-14
CD27 antigenAssay added to human services.13-Jan-14
ClusterinAssay moved to a different multiplex. Assay dilution adjusted.13-Jan-14
Fibroblast Growth Factor 21Assay added to human services.13-Jan-14
Fibroblast Growth Factor 23Assay added to human services.13-Jan-14
Insulin-like Growth Receptor Type 1Assay added to human services.13-Jan-14
Insulin-like Growth Receptor Type 2Assay added to human services.13-Jan-14
ProgranulinAssay added to human services.13-Jan-14
Thymus-Expressed ChemokineAssay added to human services.13-Jan-14
Tissue Inhibitor of Metalloproteinsases 3Assay added to human services.13-Jan-14
VitronectinAssay moved to a different multiplex.13-Jan-14
Angiotensinogen (AGT)Assay discontinued from all human products.09-Jan-14
Apolipoprotein D (Apo D)Assay redeveloped using new antibody pair.07-Jan-14

2013

Quarter 4

AssayDescription of ChangeEffective Date
Tissue Inhibitor of Metalloproteinases 3 (TIMP-3)This assay did not meet performance specifications in Serum and results should be used for information purposes only.05-Dec-13
EzrinAssay discontinued from all human products.02-Dec-13
Malondialdehyde-Modified Low-Density Lipoprotein (MDA-LDL)This assay did not meet performance specifications and has been discontinued.19-Nov-13

Quarter 3

AssayDescription of ChangeEffective Date
Pentraxin-3 (PTX3)This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only.25-Sep-13

Quarter 2

AssayDescription of ChangeEffective Date
Cadherin-1 (E-CAD)This assay did not meet performance specifications in Serum and results should be used for information purposes only.26-Apr-13
Pancreatic secretory trypsin inhibitor (TATI)This assay did not meet performance specifications in Serum and results should be used for information purposes only.26-Apr-13
Tyrosine kinase with Ig and EGF homology domains 1 (Tie-1)This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only.26-Apr-13
Alpha-2-Macroglobulin (A2M)This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only.26-Apr-13
S100 calcium-binding protein B (S-100B)This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only.26-Apr-13
E-selectinThis assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only.26-Apr-13
EN-RAGEThis assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only.26-Apr-13

Quarter 1

AssayDescription of ChangeEffective Date
Prostate Specific Antigen, total (human)Assay adjusted to meet industry standards.14-Feb-13
MMP-2 (human)Assay discontinued from all human products.23-Jan-13
Apo-A1 (human)Updated serum and plasma ranges. Assay adjusted to meet industry standards.15-Jan-13
NGAL (rodent)Redeveloped using new antibody pair.15-Jan-13
Angiotensinogen (human)Myriad RBM range under evaluation.15-Jan-13
MMP-1 (human)Myriad RBM range under evaluation.15-Jan-13
MMP-7 (human)Myriad RBM range under evaluation.15-Jan-13
MMP-10 (human)Myriad RBM range under evaluation.15-Jan-13
MMP-9, total (human)Myriad RBM range under evaluation.15-Jan-13
Peroxiredoxin-4 (human)Assay discontinued from all human products.8-Jan-13
Protein S100 A6 (human)Assay discontinued from all human products.8-Jan-13